Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24076266 | 1.00 | POLB (0.44) | POLBLMNAHTTNPSR1MAPK8 | |
| SCHEMBL22552265 | 0.81 | POLB (0.44) | POLBMAPK8CHEK1TSHRSMN1; SMN2 | |
| SCHEMBL30319347 | 0.79 | POLB (0.40) | POLBLMNAHTTNPSR1CHEK1 | |
| SCHEMBL26738078 | 0.78 | TSHR (0.44) | POLBHTTPARP1KMT2ATSHR | |
| SCHEMBL24076922 | 0.78 | POLB (0.42) | POLBCHEK1TSHRPRMT5WDR77 | |
| SCHEMBL30231242 | 0.78 | DYRK1A (0.46) | POLBLMNATSHRPRMT5WDR77 | |
| SCHEMBL24076915 | 0.78 | DYRK1A (0.46) | POLBLMNATSHRPRMT5WDR77 | |
| SCHEMBL24076279 | 0.78 | POLB (0.42) | POLBHTTKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL16675892 | 0.78 | GSK3B (0.44) | LMNACHEK1PARP1SMN1; SMN2TP53 | |
| SCHEMBL17229811 | 0.78 | FADS1 (0.45) | LMNACHEK1KMT2AFABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261456-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2023-06-13 | — | — | CN | disclosed |