Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Udenafil. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A known ✓ | O76074 | 19/20 | 1.00 |
| ▸ | PDE2A | O00408 | 1/20 | 0.64 |
| ▸ | PDE9A | O76083 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | PDE6C | P51160 | 1/20 | 0.64 |
| ▸ | PDE1A | P54750 | 1/20 | 0.64 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.64 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Udenafil SCHEMBL120993 | 1.00 | PDE5A (1.00) | PDE5APDE2APDE9APDE4APDE6C | |
| Udenafil SCHEMBL8054822 | 0.97 | PDE5A (0.94) | PDE5APDE2APDE9APDE4APDE6C | |
| Udenafil SCHEMBL8055636 | 0.97 | PDE5A (0.94) | PDE5APDE2APDE9APDE4APDE6C | |
| Udenafil SCHEMBL8055433 | 0.97 | PDE5A (0.94) | PDE5APDE2APDE9APDE4APDE6C | |
| Udenafil SCHEMBL8055565 | 0.95 | PDE5A (0.91) | PDE5APDE2APDE9APDE4APDE6C | |
| SCHEMBL16850578 | 0.95 | PDE5A (0.91) | PDE5APDE2APDE9APDE4APDE6C | |
| Udenafil SCHEMBL8055012 | 0.94 | PDE5A (0.89) | PDE5APDE2APDE9APDE4APDE6C | |
| Udenafil SCHEMBL8055765 | 0.94 | PDE5A (0.89) | PDE5APDE2APDE9APDE4APDE6C | |
| Udenafil SCHEMBL8066232 | 0.94 | PDE5A (0.89) | PDE5APDE2APDE9APDE4APDE6C | |
| Udenafil SCHEMBL8055102 | 0.94 | PDE5A (0.89) | PDE5APDE2APDE9APDE4APDE6C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-220473989-U | RK 3568-based B2B core board | 北京神州数码有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-219181516-U | Data transmission equipment | 北京神州数码有限公司 | 2023-06-13 | — | — | CN | claimed |
| CN-222213452-U | Store bill printer with code scanning function | 浙江魔杰电子股份有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-220798296-U | Modbus-based network communication device | 陕西天极星控信息技术有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-220473989-U | RK 3568-based B2B core board | 北京神州数码有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-219181516-U | Data transmission equipment | 北京神州数码有限公司 | 2023-06-13 | — | — | CN | disclosed |