Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257720 | 1.00 | FYN (0.44) | FYNGRM5DHFRNUDT1ADORA1 | |
| SCHEMBL24257765 | 0.80 | GRM5 (0.42) | FYNGRM5ADORA1ADORA2A | |
| SCHEMBL30453193 | 0.80 | GRM5 (0.42) | FYNGRM5ADORA1ADORA2A | |
| SCHEMBL30454648 | 0.79 | DHFR (0.44) | DHFRNUDT1ADORA1LRRK2ADORA2A | |
| SCHEMBL24257698 | 0.79 | DHFR (0.44) | DHFRNUDT1ADORA1LRRK2ADORA2A | |
| SCHEMBL24257691 | 0.75 | USP7 (0.51) | DHFRNUDT1ADORA1LRRK2ADORA2A | |
| SCHEMBL30453863 | 0.75 | LRRK2 (0.43) | GRM5DHFRNUDT1ADORA1LRRK2 | |
| SCHEMBL24257841 | 0.75 | LRRK2 (0.43) | GRM5DHFRNUDT1ADORA1LRRK2 | |
| SCHEMBL30452753 | 0.75 | USP7 (0.51) | DHFRNUDT1ADORA1LRRK2ADORA2A | |
| SCHEMBL24257639 | 0.73 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196466-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |