Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 16/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SGK3 | Q96BR1 | 1/20 | 0.35 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488075 | 1.00 | SGK1 (0.38) | SGK1CSF1RPIK3CDPIK3CAPIK3CB | |
| SCHEMBL488278 | 0.92 | CSF1R (0.38) | SGK1CSF1RPIK3CDPIK3CAPIK3CB | |
| SCHEMBL30453586 | 0.92 | CSF1R (0.38) | SGK1CSF1RPIK3CDPIK3CAPIK3CB | |
| SCHEMBL30452950 | 0.90 | TYRO3 (0.41) | CSF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL488712 | 0.90 | TYRO3 (0.41) | CSF1RPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30453554 | 0.85 | MET (0.44) | SGK1CYP3A4SGK3SGK2MET | |
| SCHEMBL488469 | 0.85 | MET (0.44) | SGK1CYP3A4SGK3SGK2MET | |
| SCHEMBL487959 | 0.84 | MET (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGSGK2 | |
| SCHEMBL30453227 | 0.84 | MET (0.45) | PIK3CDPIK3CAPIK3CBPIK3CGSGK2 | |
| SCHEMBL488429 | 0.83 | MET (0.49) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |