Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23879245 | 1.00 | MAPT (0.44) | MAPTKMT2AGLAMEN1SMN1; SMN2 | |
| SCHEMBL30452606 | 1.00 | MAPT (0.44) | MAPTKMT2AGLAMEN1SMN1; SMN2 | |
| SCHEMBL30452491 | 0.90 | CA12 (0.47) | MAPTKMT2ASMN1; SMN2RAB9ALMNA | |
| SCHEMBL23879266 | 0.90 | CA12 (0.47) | MAPTKMT2ASMN1; SMN2RAB9ALMNA | |
| SCHEMBL4318037 | 0.83 | MAPT (0.37) | MAPTKMT2AGLAMEN1SMN1; SMN2 | |
| SCHEMBL23879232 | 0.81 | ALDH1A1 (0.49) | MAPTKMT2AGLAMEN1SMN1; SMN2 | |
| SCHEMBL30452578 | 0.81 | ALDH1A1 (0.49) | MAPTKMT2AGLAMEN1SMN1; SMN2 | |
| SCHEMBL23879233 | 0.74 | PLAU (0.37) | MAPTKMT2ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL30452681 | 0.74 | PLAU (0.37) | MAPTKMT2ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL23879240 | 0.73 | TSHR (0.41) | MAPTKMT2AMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253404-B | Nitrogen-containing heterocyclic compound and composition, preparation method and application thereof | 上海医药集团股份有限公司 | 2023-05-23 | — | — | CN | disclosed |