Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488225 | 1.00 | TYRO3 (0.42) | TYRO3PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL488712 | 0.92 | TYRO3 (0.41) | TYRO3PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL30452950 | 0.92 | TYRO3 (0.41) | TYRO3PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL30453586 | 0.90 | CSF1R (0.38) | PIK3CDPIK3CAPIK3CGPIK3CBCSF1R | |
| SCHEMBL488278 | 0.90 | CSF1R (0.38) | PIK3CDPIK3CAPIK3CGPIK3CBCSF1R | |
| SCHEMBL30453720 | 0.85 | MET (0.41) | JAK2 | |
| SCHEMBL487812 | 0.85 | MET (0.41) | JAK2 | |
| SCHEMBL487930 | 0.85 | MAP4K4 (0.45) | TYRO3PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL488736 | 0.85 | TYRO3 (0.42) | TYRO3PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL30454893 | 0.85 | MAP4K4 (0.45) | TYRO3PIK3CDPIK3CAPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |