Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 3/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.38 |
| ▸ | TUBB | P07437 | 3/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037531 | 1.00 | TFPI2 (0.50) | TFPI2TUBB1ACHETUBB4ATUBB | |
| SCHEMBL28683546 | 0.88 | TFPI2 (0.40) | TFPI2TUBB1ACHETUBB4ATUBB | |
| SCHEMBL12068038 | 0.82 | TFPI2 (0.53) | TFPI2TUBB1ACHETUBB4ATUBB | |
| SCHEMBL28661147 | 0.81 | TFPI2 (0.52) | TFPI2TUBB1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30454134 | 0.81 | TUBB1 (0.59) | TFPI2TUBB1HDAC1HDAC6CYP1A2 | |
| SCHEMBL28683537 | 0.81 | TUBB1 (0.59) | TFPI2TUBB1HDAC1HDAC6CYP1A2 | |
| SCHEMBL20022021 | 0.76 | TFPI2 (0.47) | TFPI2TUBB1ACHETUBB4ATUBB | |
| SCHEMBL3919425 | 0.75 | TUBB1 (0.74) | TFPI2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL31517159 | 0.74 | TFPI2 (0.48) | TFPI2TUBB1 | |
| SCHEMBL3421643 | 0.74 | NOTUM (0.39) | TFPI2ACHEKMT2ATP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912529-B | Method for synthesizing indole compounds by catalyzing N-aryl amide compounds and vinylene carbonate with ruthenium | 成都大学 | 2023-07-25 | — | — | CN | disclosed |