Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.35 |
| ▸ | TUBB | P07437 | 4/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12068038 | 0.83 | TFPI2 (0.53) | TFPI2TUBB1ACHETUBB4ATUBB | |
| SCHEMBL29037531 | 0.76 | TFPI2 (0.50) | TFPI2TUBB1ACHETUBB4ATUBB | |
| SCHEMBL30452525 | 0.76 | TFPI2 (0.50) | TFPI2TUBB1ACHETUBB4ATUBB | |
| SCHEMBL3919425 | 0.72 | TUBB1 (0.74) | TFPI2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL5083180 | 0.72 | TUBB4A (0.49) | TFPI2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL20977900 | 0.71 | NOTUM (0.46) | TFPI2TUBB1ACHETUBB4ATUBB | |
| SCHEMBL31316166 | 0.71 | NOTUM (0.46) | TFPI2TUBB1ACHETUBB4ATUBB | |
| SCHEMBL13547876 | 0.70 | PRKCI (0.55) | TUBB1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL14115781 | 0.69 | NOTUM (0.44) | TFPI2TUBB1ACHETUBB4ATUBB | |
| SCHEMBL31316159 | 0.68 | TDP1 (0.47) | TFPI2TUBB1ACHEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180092822-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | L'OREAL (FR) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180092822-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | KRT18, TYR, INCENP | TFPI2 3191/4885TUBB1 147/4885ACHE 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.