SCHEMBL30452532

SCHEMBL30452532

Nc1ncc(-c2ccc(C(=O)N3CCC[C@H]3CN3CCCC3)cc2)cc1OCc1c(F)cccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MET P08581 14/20 1.00
CSF1R P07333 2/20 0.66
ALK Q9UM73 4/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL488321 1.00 MET (1.00) METCSF1RALK
SCHEMBL30452699 1.00 MET (1.00) METCSF1RALK
SCHEMBL6417569 1.00 MET (1.00) METCSF1RALK
SCHEMBL487774 1.00 MET (1.00) METCSF1RALK
SCHEMBL487623 0.95 MET (1.00) METCSF1RALK
SCHEMBL487952 0.95 MET (1.00) METCSF1RALK
SCHEMBL489386 0.95 MET (1.00) METCSF1RALK
SCHEMBL30452772 0.95 MET (1.00) METCSF1RALK
SCHEMBL30452653 0.95 MET (0.90) METCSF1RALK
SCHEMBL30453496 0.95 MET (1.00) METCSF1RALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113181362-B Medicament for preventing and/or treating amyotrophic lateral sclerosis 国立大学法人京都大学 2023-06-13 CN disclosed