Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.48 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.48 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | MERTK | Q12866 | 2/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487715 | 1.00 | MET (0.66) | METKCNH2MAP4K4BMPR1BBMPR1A | |
| SCHEMBL487697 | 0.94 | MET (0.65) | METKCNH2MAP4K4BMPR1BBMPR1A | |
| SCHEMBL27650119 | 0.90 | MET (0.54) | METKCNH2MAP4K4BMPR1BBMPR1A | |
| SCHEMBL30453079 | 0.87 | MET (0.63) | METKCNH2MAP4K4BMPR1BBMPR1A | |
| SCHEMBL488445 | 0.87 | MET (0.63) | METKCNH2MAP4K4BMPR1BBMPR1A | |
| SCHEMBL30453219 | 0.87 | MET (0.68) | METKCNH2MAP4K4 | |
| SCHEMBL488476 | 0.87 | MET (0.68) | METKCNH2MAP4K4 | |
| SCHEMBL14631832 | 0.87 | MET (0.68) | METKCNH2MAP4K4 | |
| SCHEMBL487781 | 0.87 | MET (0.69) | METMAP4K4MERTKAXLATR | |
| SCHEMBL30454983 | 0.87 | MET (0.69) | METMAP4K4MERTKAXLATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |