Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.52 |
| ▸ | MAP4K3 | Q8IVH8 | 4/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10215491 | 1.00 | MET (0.52) | METMAP4K3JAK2PIK3CAMTOR | |
| SCHEMBL488176 | 1.00 | MET (0.52) | METMAP4K3JAK2PIK3CAMTOR | |
| SCHEMBL30454688 | 0.86 | MET (0.49) | METMAP4K3JAK2KDM4ENPC1 | |
| SCHEMBL487709 | 0.86 | MET (0.49) | METMAP4K3JAK2KDM4ENPC1 | |
| SCHEMBL30452803 | 0.85 | MET (0.69) | METMAP4K3JAK2 | |
| SCHEMBL10215375 | 0.85 | MET (0.69) | METMAP4K3JAK2 | |
| SCHEMBL487998 | 0.85 | MET (0.69) | METMAP4K3JAK2 | |
| SCHEMBL30453871 | 0.85 | MET (0.42) | METMAP4K3JAK2PIK3CAMTOR | |
| SCHEMBL488396 | 0.85 | MET (0.42) | METMAP4K3JAK2PIK3CAMTOR | |
| SCHEMBL10215391 | 0.83 | MET (0.58) | METMAP4K3JAK2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |