Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488126 | 1.00 | MET (0.57) | METMAP4K4JAK2MAP4K3SCN1A | |
| SCHEMBL488519 | 0.99 | MET (0.56) | METMAP4K4JAK2MAP4K3SCN1A | |
| SCHEMBL30453320 | 0.99 | MET (0.56) | METMAP4K4JAK2MAP4K3SCN1A | |
| SCHEMBL487986 | 0.93 | MET (0.53) | METMAP4K4JAK2MAP4K3 | |
| SCHEMBL30453401 | 0.93 | MET (0.53) | METMAP4K4JAK2MAP4K3 | |
| SCHEMBL30452637 | 0.91 | MET (0.54) | METJAK2MAP4K3 | |
| SCHEMBL488277 | 0.91 | MET (0.54) | METJAK2MAP4K3 | |
| SCHEMBL30452745 | 0.91 | MET (0.51) | METMAP4K4JAK2MAP4K3 | |
| SCHEMBL488343 | 0.91 | MET (0.51) | METMAP4K4JAK2MAP4K3 | |
| SCHEMBL488056 | 0.90 | MET (0.51) | METMAP4K4JAK2MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |