Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 5/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487586 | 1.00 | MET (0.48) | METJAK2MAP4K3MPOICMT | |
| SCHEMBL487937 | 0.89 | MET (0.53) | METJAK2MAP4K3MPOICMT | |
| SCHEMBL488123 | 0.89 | MET (0.49) | METICMTSOS1S1PR1MAP3K11 | |
| SCHEMBL30453435 | 0.89 | MET (0.49) | METICMTSOS1S1PR1MAP3K11 | |
| SCHEMBL487640 | 0.89 | MET (0.52) | METJAK2MAP4K3MPOICMT | |
| SCHEMBL487928 | 0.88 | MET (0.40) | METMPOICMTSOS1S1PR1 | |
| SCHEMBL30453537 | 0.88 | MET (0.40) | METMPOICMTSOS1S1PR1 | |
| SCHEMBL487675 | 0.87 | MET (0.47) | METJAK2MAP4K3MPOS1PR1 | |
| SCHEMBL487845 | 0.85 | MET (0.48) | METJAK2MAP4K3SOS1S1PR1 | |
| SCHEMBL10215218 | 0.84 | MET (0.45) | METJAK2MAP4K3MPOICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |