Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 9/20 | 0.37 |
| ▸ | HTR2B | P41595 | 7/20 | 0.37 |
| ▸ | HTR2A | P28223 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE8B | O95263 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29015610 | 1.00 | TP53 (0.41) | TP53HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL20855753 | 0.74 | TP53 (0.43) | TP53HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL20855751 | 0.74 | TP53 (0.43) | TP53HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL30452007 | 0.74 | TTR (0.32) | TTR | |
| SCHEMBL29015546 | 0.74 | TTR (0.32) | TTR | |
| SCHEMBL14833093 | 0.71 | HTR2C (0.50) | HTR2CHTR2BHTR2ATSHRHPGD | |
| SCHEMBL24252872 | 0.71 | PTGDR2 (0.46) | TP53ALDH1A1 | |
| SCHEMBL13651802 | 0.69 | TP53 (0.39) | TP53HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL12309442 | 0.68 | KDM1A (0.47) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL1093945 | 0.68 | HTR2C (0.61) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |