Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16812488 | 0.94 | TYK2 (0.40) | TYK2MEN1KMT2ANR3C1SSTR3 | |
| SCHEMBL16794640 | 0.94 | TYK2 (0.40) | TYK2MEN1KMT2ANR3C1SSTR3 | |
| SCHEMBL26101957 | 0.94 | TYK2 (0.40) | TYK2MEN1KMT2ANR3C1SSTR3 | |
| SCHEMBL16794641 | 0.94 | TYK2 (0.40) | TYK2MEN1KMT2ANR3C1SSTR3 | |
| SCHEMBL31161788 | 0.88 | TYK2 (0.37) | TYK2SSTR3CNR2CNR1PDE1B | |
| SCHEMBL29754467 | 0.87 | PDE1B (0.34) | MEN1KMT2ANR3C1SSTR3KAT8 | |
| SCHEMBL29754326 | 0.84 | PTPN1 (0.38) | MEN1KMT2ANR3C1PDE1B | |
| SCHEMBL16794653 | 0.83 | CNR2 (0.41) | TYK2CNR2CNR1 | |
| SCHEMBL31161333 | 0.83 | SSTR3 (0.35) | TYK2MEN1KMT2ANR3C1SSTR3 | |
| SCHEMBL26101467 | 0.83 | TYK2 (0.40) | TYK2SSTR3KAT8CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916207-A | Five-membered and six-membered heterocyclic compounds and application thereof as protein receptor kinase inhibitors | 轶诺(浙江)药业有限公司 | 2023-04-04 | — | — | CN | disclosed |