Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 3/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 7/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794676 | 0.93 | PDE1B (0.40) | PTPN1CCR2PDE1BNR3C1ALDH1A1 | |
| SCHEMBL31245703 | 0.89 | MAPT (0.40) | PDE1BALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL18161034 | 0.85 | PDE1B (0.41) | PTPN1PDE1BNR3C1ALDH1A1HTT | |
| SCHEMBL24263381 | 0.84 | PDE1B (0.39) | PTPN1PDE1BNR3C1ALDH1A1HTT | |
| SCHEMBL30452720 | 0.84 | TYK2 (0.39) | PDE1BNR3C1MEN1KMT2A | |
| SCHEMBL3017547 | 0.84 | BCL2A1 (0.40) | CCR2PDE1BNR3C1SMN1; SMN2TAS2R14 | |
| SCHEMBL26102728 | 0.84 | MAPT (0.41) | PTPN1CCR2PDE1BNR3C1ALDH1A1 | |
| SCHEMBL16812352 | 0.83 | PDE1B (0.38) | PDE1BNR3C1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16794693 | 0.82 | MAPT (0.42) | PDE1BALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL16812355 | 0.81 | ALDH1A1 (0.39) | PDE1BNR3C1ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240335443-A1 | IMIDAZOLOPYRIDAZINE OR PYRAZOLOPYRIMIDINE COMPOUNDS AND COMPOSITIONS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2024-10-10 | — | — | US | disclosed |
| EP-4281458-A1 | IMIDAZOLOPYRIDAZINE OR PYRAZOLOPYRIMIDINE COMPOUNDS AND COMPOSITIONS | Anrui Biomedical Technology (Guangzhou) Co., Ltd. (CN) | 2023-11-29 | — | — | EP | disclosed |
| CN-115916207-A | Five-membered and six-membered heterocyclic compounds and application thereof as protein receptor kinase inhibitors | 轶诺(浙江)药业有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2022156657-A1 | IMIDAZOLOPYRIDAZINE OR PYRAZOLOPYRIMIDINE COMPOUNDS AND COMPOSITIONS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2022-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335443-A1 | IMIDAZOLOPYRIDAZINE OR PYRAZOLOPYRIMIDINE COMPOUNDS AND COMPOSITIONS | TYK2, PTK2B, JAK1 | PTPN1 178/4885CCR2 949/4885PDE1B 918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.