Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.41 |
| ▸ | MET | P08581 | 4/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | SGK1 | O00141 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488100 | 1.00 | CSF1R (0.41) | CSF1RMETJAK2JAK3MAP4K4 | |
| SCHEMBL30452621 | 0.95 | CSF1R (0.40) | CSF1RMETJAK2JAK3MAP4K4 | |
| SCHEMBL488165 | 0.95 | CSF1R (0.40) | CSF1RMETJAK2JAK3MAP4K4 | |
| SCHEMBL30452628 | 0.92 | TYRO3 (0.40) | CSF1RMETMAP4K4PIK3CDPIK3CA | |
| SCHEMBL488554 | 0.92 | TYRO3 (0.40) | CSF1RMETMAP4K4PIK3CDPIK3CA | |
| SCHEMBL487892 | 0.91 | MAP4K4 (0.43) | CSF1RMETMAP4K4ACVR1SGK1 | |
| SCHEMBL30453605 | 0.91 | MAP4K4 (0.43) | CSF1RMETMAP4K4ACVR1SGK1 | |
| SCHEMBL487716 | 0.91 | MAP4K4 (0.44) | CSF1RMETMAP4K4ACVR1SGK1 | |
| SCHEMBL30453212 | 0.91 | MAP4K4 (0.44) | CSF1RMETMAP4K4ACVR1SGK1 | |
| SCHEMBL30454955 | 0.89 | MAP4K4 (0.46) | CSF1RMETJAK2MAP4K4ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |