Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10316727 | 1.00 | MET (0.66) | METKCNH2JAK2MAP4K3KDM1A | |
| SCHEMBL487983 | 1.00 | MET (0.66) | METKCNH2JAK2MAP4K3KDM1A | |
| SCHEMBL30452989 | 1.00 | MET (0.66) | METKCNH2JAK2MAP4K3KDM1A | |
| SCHEMBL488021 | 1.00 | MET (0.66) | METKCNH2JAK2MAP4K3KDM1A | |
| SCHEMBL30454369 | 0.95 | MET (0.68) | METJAK2MAP4K3 | |
| SCHEMBL488261 | 0.95 | MET (0.68) | METJAK2MAP4K3 | |
| SCHEMBL487691 | 0.91 | MET (0.56) | METKCNH2JAK2MAP4K3KDM1A | |
| SCHEMBL30453731 | 0.91 | MET (0.56) | METKCNH2JAK2MAP4K3KDM1A | |
| SCHEMBL487971 | 0.91 | MET (0.56) | METKCNH2JAK2MAP4K3KDM1A | |
| SCHEMBL30453464 | 0.91 | MET (0.56) | METKCNH2JAK2MAP4K3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |