Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.46 |
| ▸ | ATR | Q13535 | 5/20 | 0.41 |
| ▸ | CSF1R | P07333 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | MET | P08581 | 4/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488090 | 1.00 | MAP4K4 (0.46) | MAP4K4ATRCSF1RSRCMET | |
| SCHEMBL30454893 | 0.99 | MAP4K4 (0.45) | MAP4K4ATRCSF1RSRCMET | |
| SCHEMBL487930 | 0.99 | MAP4K4 (0.45) | MAP4K4ATRCSF1RSRCMET | |
| SCHEMBL30453752 | 0.93 | MAP4K4 (0.47) | MAP4K4ATRCSF1RMETTYRO3 | |
| SCHEMBL488377 | 0.93 | MAP4K4 (0.47) | MAP4K4ATRCSF1RMETTYRO3 | |
| SCHEMBL30452628 | 0.92 | TYRO3 (0.40) | MAP4K4ATRCSF1RMETTYRO3 | |
| SCHEMBL488554 | 0.92 | TYRO3 (0.40) | MAP4K4ATRCSF1RMETTYRO3 | |
| SCHEMBL30453212 | 0.91 | MAP4K4 (0.44) | MAP4K4ATRCSF1RSRCMET | |
| SCHEMBL487716 | 0.91 | MAP4K4 (0.44) | MAP4K4ATRCSF1RSRCMET | |
| SCHEMBL487838 | 0.90 | CSF1R (0.40) | MAP4K4ATRCSF1RMETTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |