Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.65 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488328 | 1.00 | MET (0.65) | METALKCNR1SMN1; SMN2JAK2 | |
| SCHEMBL488354 | 0.96 | MET (0.71) | METALKJAK2AXL | |
| SCHEMBL30452863 | 0.96 | MET (0.71) | METALKJAK2AXL | |
| SCHEMBL487919 | 0.93 | MET (0.74) | METALKCNR1JAK2AXL | |
| SCHEMBL30452751 | 0.93 | MET (0.74) | METALKCNR1JAK2AXL | |
| SCHEMBL30452627 | 0.90 | MET (0.80) | METALKJAK2 | |
| SCHEMBL488578 | 0.90 | MET (0.80) | METALKJAK2 | |
| SCHEMBL30453991 | 0.89 | MET (0.81) | METALKJAK2AXL | |
| SCHEMBL487939 | 0.89 | MET (0.81) | METALKJAK2AXL | |
| SCHEMBL488395 | 0.86 | CNR1 (0.49) | METALKCNR1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |