Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 10/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HPGDS | O60760 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487776 | 1.00 | MET (0.56) | METCD274HPGDHPGDSALDH1A1 | |
| SCHEMBL30454410 | 0.95 | MET (0.55) | METCD274HPGDALDH1A1 | |
| SCHEMBL488059 | 0.95 | MET (0.55) | METCD274HPGDALDH1A1 | |
| SCHEMBL30452636 | 0.91 | MET (0.56) | METCD274HPGDALDH1A1HTR1A | |
| SCHEMBL487659 | 0.91 | MET (0.56) | METCD274HPGDALDH1A1HTR1A | |
| SCHEMBL30453287 | 0.90 | CD274 (0.58) | METCD274HPGDALDH1A1HTR1A | |
| SCHEMBL488424 | 0.90 | CD274 (0.58) | METCD274HPGDALDH1A1HTR1A | |
| SCHEMBL487760 | 0.89 | MET (0.58) | METCD274HPGDHPGDS | |
| SCHEMBL487702 | 0.88 | MET (0.57) | METCD274HPGDHPGDS | |
| SCHEMBL30454041 | 0.88 | MET (0.57) | METCD274HPGDHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |