Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | F12 | P00748 | 1/20 | 0.52 |
| ▸ | F11 | P03951 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25840713 | 0.78 | PLG (0.37) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL24252266 | 0.78 | PLG (0.67) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL30467809 | 0.76 | PDE10A (0.46) | DHFRLRRK2PDE10A | |
| SCHEMBL24252260 | 0.76 | PDE10A (0.46) | DHFRLRRK2PDE10A | |
| SCHEMBL25840702 | 0.75 | PLG (0.34) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL25840905 | 0.75 | PLG (0.35) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL24252686 | 0.74 | LRRK2 (0.35) | ENPP2DHFRLRRK2PDE10A | |
| SCHEMBL24252292 | 0.74 | PLG (0.34) | PLGF12F11KLKB1PRSS1 | |
| SCHEMBL24252672 | 0.74 | FEN1 (0.36) | KDM4EALDH1A1PDE10A | |
| SCHEMBL24252270 | 0.74 | PDE10A (0.36) | DHFRLRRK2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |