Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 5/20 | 0.53 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 3/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488822 | 1.00 | ATR (0.53) | ATRCSF1RFYNMETERN1 | |
| SCHEMBL30453528 | 0.91 | KCNH2 (0.53) | ATRCSF1RMETKCNH2AURKA | |
| SCHEMBL488017 | 0.91 | KCNH2 (0.53) | ATRCSF1RMETKCNH2AURKA | |
| SCHEMBL30453351 | 0.86 | ATR (0.56) | ATRCSF1RMETAXLMERTK | |
| SCHEMBL488097 | 0.86 | ATR (0.56) | ATRCSF1RMETAXLMERTK | |
| SCHEMBL10216291 | 0.86 | MET (0.48) | ATRCSF1RMET | |
| SCHEMBL487807 | 0.86 | MET (0.48) | ATRCSF1RMET | |
| SCHEMBL487949 | 0.86 | KCNH2 (0.47) | ATRCSF1RMETKCNH2 | |
| SCHEMBL30453684 | 0.86 | KCNH2 (0.47) | ATRCSF1RMETKCNH2 | |
| SCHEMBL488252 | 0.86 | KCNH2 (0.47) | ATRCSF1RMETKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |