Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.66 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.62 |
| ▸ | MERTK | Q12866 | 4/20 | 0.57 |
| ▸ | AXL | P30530 | 3/20 | 0.57 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.56 |
| ▸ | ATR | Q13535 | 1/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.50 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.49 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488613 | 1.00 | MET (0.66) | METMAP4K4MERTKAXLAVPR2 | |
| SCHEMBL10216178 | 0.97 | MET (0.63) | METMAP4K4MERTKAXLAVPR2 | |
| SCHEMBL10217468 | 0.96 | MET (0.62) | METMAP4K4MERTKAXLAVPR2 | |
| SCHEMBL10217711 | 0.95 | MET (0.60) | METMAP4K4MERTKAXLAVPR2 | |
| SCHEMBL10217566 | 0.93 | MET (0.61) | METMAP4K4MERTKAXLAVPR2 | |
| SCHEMBL19610827 | 0.92 | MERTK (0.59) | METMAP4K4MERTKAXLAVPR2 | |
| SCHEMBL10217467 | 0.92 | MET (0.56) | METMAP4K4MERTKAXLAVPR2 | |
| SCHEMBL10217479 | 0.92 | MET (0.59) | METMAP4K4MERTKAXLAVPR2 | |
| SCHEMBL10217780 | 0.91 | MET (0.58) | METMAP4K4MERTKAXLAVPR2 | |
| SCHEMBL10217502 | 0.91 | MET (0.62) | METMAP4K4MERTKAXLAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |