Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.55 |
| ▸ | JAK2 | O60674 | 11/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.44 |
| ▸ | JAK1 | P23458 | 3/20 | 0.40 |
| ▸ | TYK2 | P29597 | 3/20 | 0.40 |
| ▸ | JAK3 | P52333 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488060 | 1.00 | MET (0.55) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL26916966 | 0.87 | MET (0.60) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL26916970 | 0.87 | MET (0.60) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL30453715 | 0.86 | MET (0.69) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL488617 | 0.86 | MET (0.69) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL15273909 | 0.85 | MET (0.56) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL26916840 | 0.83 | MET (0.52) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL26916845 | 0.83 | MET (0.52) | METJAK2ALKJAK1TYK2 | |
| SCHEMBL29857933 | 0.83 | MET (0.68) | METJAK2ALK | |
| SCHEMBL26916852 | 0.83 | MET (0.68) | METJAK2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |