Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488203 | 1.00 | MET (0.61) | METNR1H4MAP4K4SRD5A2KDM4E | |
| SCHEMBL30452851 | 0.88 | MET (0.56) | METNR1H4KDM4EALDH1A1HPGD | |
| SCHEMBL488122 | 0.88 | MET (0.56) | METNR1H4KDM4EALDH1A1HPGD | |
| SCHEMBL487621 | 0.84 | MET (0.52) | MET | |
| SCHEMBL30452497 | 0.84 | MET (0.52) | MET | |
| SCHEMBL5484750 | 0.83 | MET (0.58) | METNR1H4 | |
| SCHEMBL487846 | 0.83 | MET (0.50) | MET | |
| SCHEMBL30453573 | 0.83 | MET (0.50) | MET | |
| SCHEMBL27650107 | 0.82 | MET (0.60) | METNR1H4MAP4K4MPO | |
| SCHEMBL487484 | 0.82 | MET (0.51) | METKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |