Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487815 | 1.00 | MET (0.40) | METACVR1FYNTGFBR1RIPK2 | |
| SCHEMBL14492528 | 0.93 | MET (0.42) | METACVR1FYNTGFBR1RIPK2 | |
| SCHEMBL30453720 | 0.92 | MET (0.41) | METACVR1FYNTGFBR1RIPK2 | |
| SCHEMBL487812 | 0.92 | MET (0.41) | METACVR1FYNTGFBR1RIPK2 | |
| SCHEMBL30453227 | 0.91 | MET (0.45) | METACVR1RIPK2NOD2JAK2 | |
| SCHEMBL487959 | 0.91 | MET (0.45) | METACVR1RIPK2NOD2JAK2 | |
| SCHEMBL30452950 | 0.86 | TYRO3 (0.41) | JAK2 | |
| SCHEMBL488712 | 0.86 | TYRO3 (0.41) | JAK2 | |
| SCHEMBL30452745 | 0.83 | MET (0.51) | METACVR1FYNTGFBR1RIPK2 | |
| SCHEMBL488343 | 0.83 | MET (0.51) | METACVR1FYNTGFBR1RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |