Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252683 | 1.00 | DHFR (0.36) | DHFRESR1ESR2PDE10AIDO1 | |
| SCHEMBL26771385 | 0.92 | DHFR (0.35) | DHFRESR1ESR2PDE10AIDO1 | |
| SCHEMBL24252259 | 0.87 | DHFR (0.42) | DHFRPDE10APLAUPLG | |
| SCHEMBL24252484 | 0.83 | ABL1 (0.46) | PDE10APLAUABL1PLG | |
| SCHEMBL30451992 | 0.83 | ABL1 (0.46) | PDE10APLAUABL1PLG | |
| Formic Acid SCHEMBL25257239 | 0.82 | DHFR (0.39) | DHFRPDE10APLAUPLG | |
| Formic Acid SCHEMBL30452356 | 0.82 | DHFR (0.39) | DHFRPDE10APLAUPLG | |
| SCHEMBL30451917 | 0.81 | PDE10A (0.42) | DHFRPDE10A | |
| SCHEMBL24252302 | 0.81 | PDE10A (0.42) | DHFRPDE10A | |
| SCHEMBL26771035 | 0.79 | DHFR (0.41) | DHFRPDE10APLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |