Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488183 | 1.00 | FYN (0.43) | FYNMAP4K4ATRUSP7IKBKB | |
| SCHEMBL30453701 | 0.89 | MAP4K4 (0.43) | FYNMAP4K4ATRUSP7IKBKB | |
| SCHEMBL487694 | 0.89 | MAP4K4 (0.43) | FYNMAP4K4ATRUSP7IKBKB | |
| SCHEMBL30452760 | 0.87 | IKBKB (0.48) | FYNMAP4K4ATRUSP7IKBKB | |
| SCHEMBL488201 | 0.87 | MAP4K4 (0.53) | FYNMAP4K4ATRUSP7IKBKB | |
| SCHEMBL30453319 | 0.87 | MAP4K4 (0.53) | FYNMAP4K4ATRUSP7IKBKB | |
| SCHEMBL488270 | 0.87 | IKBKB (0.48) | FYNMAP4K4ATRUSP7IKBKB | |
| SCHEMBL487724 | 0.80 | KCNH2 (0.45) | MAP4K4TGFBR1ACVR1AXLMERTK | |
| SCHEMBL487629 | 0.78 | MET (0.51) | FYNMAP4K4ATRUSP7IKBKB | |
| SCHEMBL487646 | 0.73 | MET (0.67) | FYNMAP4K4USP7TGFBR1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |