Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 9/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487826 | 1.00 | MET (0.48) | METBTKATRABCB1TLR9 | |
| SCHEMBL30453573 | 0.90 | MET (0.50) | METABCB1 | |
| SCHEMBL487846 | 0.90 | MET (0.50) | METABCB1 | |
| SCHEMBL10215231 | 0.88 | MET (0.48) | METBTKABCB1 | |
| SCHEMBL30452497 | 0.86 | MET (0.52) | METABCB1 | |
| SCHEMBL487621 | 0.86 | MET (0.52) | METABCB1 | |
| SCHEMBL488164 | 0.85 | MET (0.61) | METATR | |
| SCHEMBL30453385 | 0.85 | MET (0.61) | METATR | |
| SCHEMBL30454114 | 0.85 | MET (0.61) | METATR | |
| SCHEMBL487911 | 0.85 | MET (0.61) | METATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |