Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 16/20 | 0.58 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.57 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488464 | 1.00 | MET (0.58) | METMAP4K3CHEK2ALKJAK2 | |
| SCHEMBL1900159 | 1.00 | MET (0.58) | METMAP4K3CHEK2ALKJAK2 | |
| SCHEMBL30452752 | 0.94 | MET (0.51) | METMAP4K3CHEK2 | |
| SCHEMBL488687 | 0.94 | MET (0.51) | METMAP4K3CHEK2 | |
| SCHEMBL5486835 | 0.92 | MET (0.58) | METMAP4K3CHEK2ALKJAK2 | |
| SCHEMBL488495 | 0.92 | MET (0.58) | METMAP4K3CHEK2ALKJAK2 | |
| SCHEMBL488216 | 0.90 | MET (0.58) | METMAP4K3ALKJAK2 | |
| SCHEMBL30453109 | 0.90 | MET (0.58) | METMAP4K3ALKJAK2 | |
| SCHEMBL5486840 | 0.88 | MAP4K3 (0.62) | METMAP4K3ALKJAK2 | |
| SCHEMBL30452717 | 0.87 | MET (0.60) | METMAP4K3CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |