Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.71 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488406 | 1.00 | MET (0.71) | METALKJAK2AXL | |
| SCHEMBL30452930 | 0.96 | MET (0.78) | METALKJAK2AXL | |
| SCHEMBL488563 | 0.96 | MET (0.78) | METALKJAK2AXL | |
| SCHEMBL488639 | 0.96 | MET (0.77) | METALKJAK2AXL | |
| SCHEMBL30454143 | 0.96 | MET (0.77) | METALKJAK2AXL | |
| SCHEMBL488253 | 0.92 | MET (0.83) | METALKJAK2AXL | |
| SCHEMBL30453602 | 0.92 | MET (0.83) | METALKJAK2AXL | |
| SCHEMBL487752 | 0.91 | MET (0.85) | METALKJAK2AXL | |
| SCHEMBL30453645 | 0.91 | MET (0.85) | METALKJAK2AXL | |
| SCHEMBL488344 | 0.90 | MET (0.65) | METJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |