Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 12/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487655 | 1.00 | MET (0.64) | METUSP2HPGDKCNH2MAP4K4 | |
| SCHEMBL488239 | 0.93 | MET (0.64) | METUSP2HPGDKCNH2MAP4K4 | |
| SCHEMBL30453900 | 0.93 | MET (0.64) | METUSP2HPGDKCNH2MAP4K4 | |
| SCHEMBL30453620 | 0.92 | MET (0.55) | METKCNH2MAP4K4MAP3K11 | |
| SCHEMBL488138 | 0.92 | MET (0.55) | METKCNH2MAP4K4MAP3K11 | |
| SCHEMBL488146 | 0.90 | MET (0.63) | METHPGDKCNH2MAP4K4MAP3K11 | |
| SCHEMBL30453233 | 0.90 | MET (0.63) | METHPGDKCNH2MAP4K4MAP3K11 | |
| SCHEMBL488535 | 0.85 | MET (0.69) | MET | |
| SCHEMBL30453020 | 0.85 | MET (0.69) | MET | |
| SCHEMBL488202 | 0.85 | MET (0.66) | METKCNH2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |