Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 9/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488517 | 1.00 | MET (0.56) | METCHEK2KCNH2CSF1RATR | |
| SCHEMBL488516 | 1.00 | MET (0.56) | METCHEK2KCNH2CSF1RATR | |
| SCHEMBL10216384 | 1.00 | MET (0.56) | METCHEK2KCNH2CSF1RATR | |
| Hydrochloric Acid SCHEMBL30452583 | 0.99 | MET (0.57) | METCHEK2KCNH2CSF1RATR | |
| Hydrochloric Acid SCHEMBL488128 | 0.99 | MET (0.57) | METCHEK2KCNH2CSF1RATR | |
| Hydrochloric Acid SCHEMBL488130 | 0.99 | MET (0.57) | METCHEK2KCNH2CSF1RATR | |
| Hydrochloric Acid SCHEMBL488127 | 0.98 | MET (0.55) | METCHEK2KCNH2CSF1RATR | |
| SCHEMBL488710 | 0.93 | MET (0.50) | METCHEK2KCNH2CSF1RATR | |
| SCHEMBL30453644 | 0.93 | MET (0.50) | METCHEK2KCNH2CSF1RATR | |
| SCHEMBL488713 | 0.93 | MET (0.50) | METCHEK2KCNH2CSF1RATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |