Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30453669 | 0.93 | — | — | |
| SCHEMBL30452718 | 0.92 | — | — | |
| SCHEMBL30452600 | 0.84 | — | — | |
| SCHEMBL30453940 | 0.83 | MAPK8 (0.34) | CDK4CCNA2CCND1CDK2CCND3 | |
| SCHEMBL30453746 | 0.81 | JAK2 (0.33) | — | |
| SCHEMBL30452909 | 0.80 | JAK2 (0.30) | — | |
| SCHEMBL30453873 | 0.79 | — | — | |
| SCHEMBL30454256 | 0.78 | MAPK8 (0.33) | — | |
| SCHEMBL30453854 | 0.76 | MAPK8 (0.31) | — | |
| SCHEMBL30453269 | 0.68 | DRD2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |