Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 12/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488348 | 1.00 | MET (0.48) | METJAK2MAP4K3MAP4K4ACVR1 | |
| SCHEMBL30453699 | 0.96 | MET (0.47) | METJAK2MAP4K3MAP4K4ACVR1 | |
| SCHEMBL488155 | 0.96 | MET (0.47) | METJAK2MAP4K3MAP4K4ACVR1 | |
| SCHEMBL30452637 | 0.92 | MET (0.54) | METJAK2MAP4K3CSF1R | |
| SCHEMBL488277 | 0.92 | MET (0.54) | METJAK2MAP4K3CSF1R | |
| SCHEMBL30452745 | 0.92 | MET (0.51) | METJAK2MAP4K3MAP4K4ACVR1 | |
| SCHEMBL488343 | 0.92 | MET (0.51) | METJAK2MAP4K3MAP4K4ACVR1 | |
| SCHEMBL30454528 | 0.91 | MET (0.51) | METJAK2MAP4K3MAP4K4ACVR1 | |
| SCHEMBL488056 | 0.91 | MET (0.51) | METJAK2MAP4K3MAP4K4ACVR1 | |
| SCHEMBL30452453 | 0.90 | MET (0.46) | METJAK2MAP4K3MAP4K4ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |