Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.81 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | MERTK | Q12866 | 3/20 | 0.49 |
| ▸ | AXL | P30530 | 2/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487881 | 1.00 | MET (0.81) | METJAK2MERTKAXLLRRK2 | |
| SCHEMBL488729 | 0.95 | MET (0.83) | METJAK2MERTKAXL | |
| SCHEMBL30453919 | 0.95 | MET (0.83) | METJAK2MERTKAXL | |
| SCHEMBL487946 | 0.93 | MET (0.71) | METJAK2MERTKAXLLRRK2 | |
| SCHEMBL30453600 | 0.93 | MET (0.71) | METJAK2MERTKAXLLRRK2 | |
| SCHEMBL5256618 | 0.91 | MET (0.86) | METJAK2MERTKAXLLRRK2 | |
| SCHEMBL30452784 | 0.90 | MET (1.00) | METJAK2MERTKAXLLRRK2 | |
| SCHEMBL487888 | 0.90 | MET (1.00) | METJAK2MERTKAXLLRRK2 | |
| SCHEMBL30452768 | 0.89 | MET (0.82) | METJAK2MERTKAXLLRRK2 | |
| SCHEMBL488487 | 0.89 | MET (0.82) | METJAK2MERTKAXLLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |