Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.55 |
| ▸ | ATR | Q13535 | 4/20 | 0.53 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.45 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488214 | 1.00 | MET (0.55) | METCHEK2ATRCCNE2CCNE1 | |
| SCHEMBL30453261 | 0.92 | ATR (0.55) | METCHEK2ATRAURKAAURKB | |
| SCHEMBL489049 | 0.92 | ATR (0.55) | METCHEK2ATRAURKAAURKB | |
| SCHEMBL30454392 | 0.89 | MET (0.64) | METATRKCNH2MAP4K2MAP3K1 | |
| SCHEMBL489251 | 0.89 | MET (0.64) | METATRKCNH2MAP4K2MAP3K1 | |
| SCHEMBL488689 | 0.87 | MET (0.57) | METATRCCNE2CCNE1CDK2 | |
| SCHEMBL30453661 | 0.87 | MET (0.57) | METATRCCNE2CCNE1CDK2 | |
| SCHEMBL488665 | 0.87 | MET (0.60) | METCHEK2ATRCSF1R | |
| SCHEMBL30453101 | 0.87 | MET (0.60) | METCHEK2ATRCSF1R | |
| SCHEMBL10216384 | 0.86 | MET (0.56) | METCHEK2ATRKCNH2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |