Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 8/20 | 0.81 |
| ▸ | MET | P08581 | 11/20 | 0.61 |
| ▸ | JAK2 | O60674 | 3/20 | 0.60 |
| ▸ | AXL | P30530 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488158 | 1.00 | ALK (0.81) | ALKMETJAK2AXL | |
| SCHEMBL488800 | 0.93 | ALK (0.70) | ALKMETJAK2AXL | |
| SCHEMBL30453363 | 0.93 | ALK (0.70) | ALKMETJAK2AXL | |
| SCHEMBL17310066 | 0.92 | ALK (0.84) | ALKMETJAK2 | |
| SCHEMBL17310067 | 0.92 | ALK (0.84) | ALKMETJAK2 | |
| SCHEMBL488401 | 0.91 | ALK (0.80) | ALKMETJAK2AXL | |
| SCHEMBL30453722 | 0.91 | ALK (0.80) | ALKMETJAK2AXL | |
| SCHEMBL17310022 | 0.90 | ALK (1.00) | ALKMETJAK2 | |
| SCHEMBL15933018 | 0.90 | ALK (1.00) | ALKMETJAK2 | |
| SCHEMBL488588 | 0.88 | ALK (0.78) | ALKMETJAK2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |