Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 7/20 | 0.80 |
| ▸ | MET | P08581 | 12/20 | 0.62 |
| ▸ | JAK2 | O60674 | 3/20 | 0.60 |
| ▸ | AXL | P30530 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488401 | 1.00 | ALK (0.80) | ALKMETJAK2AXL | |
| SCHEMBL30453916 | 0.95 | ALK (0.72) | ALKMETJAK2AXL | |
| SCHEMBL487940 | 0.95 | ALK (0.72) | ALKMETJAK2AXL | |
| SCHEMBL488671 | 0.93 | MET (0.71) | ALKMETJAK2AXL | |
| SCHEMBL30454554 | 0.93 | MET (0.71) | ALKMETJAK2AXL | |
| SCHEMBL488588 | 0.92 | ALK (0.78) | ALKMETJAK2AXL | |
| SCHEMBL30453690 | 0.92 | ALK (0.78) | ALKMETJAK2AXL | |
| SCHEMBL488158 | 0.91 | ALK (0.81) | ALKMETJAK2AXL | |
| SCHEMBL30453539 | 0.91 | ALK (0.81) | ALKMETJAK2AXL | |
| SCHEMBL17310067 | 0.91 | ALK (0.84) | ALKMETJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |