Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.64 |
| ▸ | MET | P08581 | 10/20 | 0.59 |
| ▸ | MAP4K3 | Q8IVH8 | 4/20 | 0.50 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488686 | 1.00 | MAP4K4 (0.64) | MAP4K4METMAP4K3CCNCCDK8 | |
| SCHEMBL10218305 | 0.95 | MAP4K4 (0.57) | MAP4K4METMAP4K3CCNCCDK8 | |
| SCHEMBL10218213 | 0.92 | MET (0.55) | MAP4K4METMAP4K3 | |
| SCHEMBL10218212 | 0.92 | MAP4K4 (0.54) | MAP4K4METMAP4K3CCNCCDK8 | |
| SCHEMBL10218370 | 0.90 | MET (0.53) | MAP4K4METMAP4K3 | |
| SCHEMBL10218208 | 0.89 | MET (0.62) | MAP4K4METMAP4K3CCNCCDK8 | |
| SCHEMBL10218090 | 0.89 | MET (0.59) | MAP4K4METCCNCCDK8 | |
| SCHEMBL10218178 | 0.89 | MET (0.55) | MAP4K4METMAP4K3CCNCCDK8 | |
| SCHEMBL488241 | 0.89 | MET (0.52) | MAP4K4METMAP4K3CCNCCDK8 | |
| SCHEMBL10218067 | 0.88 | MET (0.53) | MAP4K4METMAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |