Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355121 | 1.00 | HCRTR1 (0.41) | HCRTR1HCRTR2PDE10AMEN1KMT2A | |
| SCHEMBL30454441 | 0.91 | PDE10A (0.42) | PDE10AMEN1KMT2AKCNJ1DRD4 | |
| SCHEMBL30454035 | 0.91 | PDE10A (0.42) | PDE10AMEN1KMT2AKCNJ1DRD4 | |
| SCHEMBL25355799 | 0.91 | PDE10A (0.42) | PDE10AMEN1KMT2AKCNJ1DRD4 | |
| SCHEMBL25355806 | 0.91 | PDE10A (0.42) | PDE10AMEN1KMT2AKCNJ1DRD4 | |
| SCHEMBL25288287 | 0.91 | PDE10A (0.42) | PDE10AMEN1KMT2AKCNJ1DRD4 | |
| SCHEMBL30453129 | 0.89 | PDE10A (0.39) | HCRTR1HCRTR2PDE10AKCNJ1DRD4 | |
| SCHEMBL25355352 | 0.89 | PDE10A (0.39) | HCRTR1HCRTR2PDE10AKCNJ1DRD4 | |
| SCHEMBL25355357 | 0.89 | PDE10A (0.39) | HCRTR1HCRTR2PDE10AKCNJ1DRD4 | |
| SCHEMBL25353543 | 0.89 | PDE10A (0.41) | PDE10AMEN1KMT2AATMKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |