Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454441 | 1.00 | PDE10A (0.42) | PDE10AKCNJ1MAPTGSK3BDRD4 | |
| SCHEMBL25288287 | 1.00 | PDE10A (0.42) | PDE10AKCNJ1MAPTGSK3BDRD4 | |
| SCHEMBL25355806 | 1.00 | PDE10A (0.42) | PDE10AKCNJ1MAPTGSK3BDRD4 | |
| SCHEMBL25355799 | 1.00 | PDE10A (0.42) | PDE10AKCNJ1MAPTGSK3BDRD4 | |
| SCHEMBL25355352 | 0.93 | PDE10A (0.39) | PDE10AKCNJ1MAPTGSK3BDRD4 | |
| SCHEMBL30453129 | 0.93 | PDE10A (0.39) | PDE10AKCNJ1MAPTGSK3BDRD4 | |
| SCHEMBL25355357 | 0.93 | PDE10A (0.39) | PDE10AKCNJ1MAPTGSK3BDRD4 | |
| SCHEMBL30453579 | 0.91 | HCRTR1 (0.41) | PDE10AKCNJ1MAPTDRD4MEN1 | |
| SCHEMBL25355121 | 0.91 | HCRTR1 (0.41) | PDE10AKCNJ1MAPTDRD4MEN1 | |
| SCHEMBL25354154 | 0.91 | PDE10A (0.42) | PDE10AKCNJ1GSK3BDRD4ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023121713-A1 | BCL-2 INHIBITORS | NEW AVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |