Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.67 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10216337 | 1.00 | MET (0.67) | METMAP4K3CHEK2ATRKCNH2 | |
| SCHEMBL30454746 | 0.95 | MET (0.74) | METMAP4K3CHEK2 | |
| SCHEMBL488862 | 0.95 | MET (0.74) | METMAP4K3CHEK2 | |
| SCHEMBL30453954 | 0.91 | MET (0.60) | METMAP4K3CHEK2ATR | |
| SCHEMBL488646 | 0.91 | MET (0.60) | METMAP4K3CHEK2ATR | |
| SCHEMBL488797 | 0.88 | MET (0.58) | METMAP4K3CHEK2ATRKCNH2 | |
| SCHEMBL30453966 | 0.88 | MET (0.58) | METMAP4K3CHEK2ATRKCNH2 | |
| SCHEMBL30453773 | 0.87 | MET (0.67) | METMAP4K3CHEK2KCNH2 | |
| SCHEMBL488338 | 0.87 | MET (0.67) | METMAP4K3CHEK2KCNH2 | |
| SCHEMBL488690 | 0.86 | KCNH2 (0.55) | METMAP4K3CHEK2ATRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |