Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15626666 | 1.00 | MAPT (0.58) | MAPTGAAPOLBLMNAADORA1 | |
| SCHEMBL30549381 | 0.85 | MAPT (0.54) | MAPTGAAPOLBLMNAADORA1 | |
| SCHEMBL15628206 | 0.84 | NR4A1 (0.53) | MAPTPOLBLMNAADORA1ABCB11 | |
| SCHEMBL4014144 | 0.83 | PARP1 (0.49) | MAPTGAAPOLBLMNAADORA1 | |
| SCHEMBL723657 | 0.82 | AKR1C3 (0.61) | MAPTGAAPOLBAKR1C3MAPK14 | |
| SCHEMBL29913321 | 0.82 | AKR1C3 (0.61) | MAPTGAAPOLBAKR1C3MAPK14 | |
| Aniline SCHEMBL28546981 | 0.81 | MAPT (0.58) | MAPTGAAPOLBLMNAAKR1C3 | |
| SCHEMBL29786713 | 0.81 | MAPT (0.74) | MAPTGAAPOLBLMNAADORA1 | |
| SCHEMBL2690787 | 0.81 | AKR1C3 (0.67) | MAPTGAAPOLBLMNAADORA1 | |
| SCHEMBL112508 | 0.81 | MAPT (0.74) | MAPTGAAPOLBLMNAADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116162065-A | Benzo [ c ] cinnoline framework diimine ligand and preparation method thereof | 中国科学院上海有机化学研究所 | 2023-05-26 | — | — | CN | disclosed |