Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | G6PD | P11413 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6355277 | 0.87 | G6PD (0.56) | AKR1C3GAAMAPTG6PDCASP7 | |
| SCHEMBL5807536 | 0.86 | MAPT (0.60) | AKR1C3GAAMAPTATMKDM4E | |
| SCHEMBL10833340 | 0.85 | PBRM1 (0.62) | AKR1C3GAAMAPTG6PDCASP7 | |
| SCHEMBL28097720 | 0.85 | AKR1C3 (0.69) | AKR1C3GAAMAPTG6PDCASP7 | |
| SCHEMBL11025929 | 0.85 | MEN1 (0.53) | AKR1C3GAAMAPTG6PDCASP7 | |
| SCHEMBL526919 | 0.85 | G6PD (0.74) | AKR1C3MAPTG6PDCASP7CASP6 | |
| SCHEMBL8656438 | 0.85 | MAPT (0.81) | AKR1C3GAAMAPTATMPOLB | |
| Hydrochloric Acid SCHEMBL27668320 | 0.85 | MAPT (0.58) | AKR1C3GAAMAPTATMKDM4E | |
| SCHEMBL29786713 | 0.84 | MAPT (0.74) | AKR1C3GAAMAPTATMPOLB | |
| SCHEMBL112508 | 0.84 | MAPT (0.74) | AKR1C3GAAMAPTATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106102477-B | Compositions with reduced bitter taste perception | 宝洁公司 | 2020-03-17 | — | — | CN | claimed |
| EP-3160592-B1 | COMPOSITIONS WITH REDUCED BITTER TASTE PERCEPTION | PROCTER & GAMBLE (US) | 2018-10-31 | — | — | EP | claimed |
| US-9827320-B2 | Compositions with reduced bitter taste perception | THE PROCTER & GAMBLE COMPANY (US) | 2017-11-28 | — | — | US | claimed |
| EP-3160592-A1 | COMPOSITIONS WITH REDUCED BITTER TASTE PERCEPTION | The Procter & Gamble Company (US) | 2017-05-03 | — | — | EP | claimed |
| CN-106102477-A | Compositions with reduced bitter taste perception | 宝洁公司 | 2016-11-09 | — | — | CN | claimed |
| WO-2015131001-A1 | COMPOSITIONS WITH REDUCED BITTER TASTE PERCEPTION | THE PROCTER & GAMBLE COMPANY (US) | 2015-09-03 | — | — | WO | claimed |
| US-20150238613-A1 | Compositions With Reduced Bitter Taste Perception | THE PROCTER & GAMBLE COMPANY | 2015-08-27 | — | — | US | claimed |
| WO-2012055170-A1 | USE OF CYTOPLASMIC C-MYC FOR REGULATING IMMUNE RESPONSES | THE UNIVERSITY OF HONG KONG (CN) | 2012-05-03 | — | — | WO | claimed |
| US-20120107317-A1 | USE OF CYTOPLASMIC C-MYC FOR REGULATING IMMUNE RESPONSES | THE UNIVERSITY OF HONG KONG (CN) | 2012-05-03 | — | — | US | claimed |
| CN-101648871-A | Optically active benzoate compound and preparation method thereof | DONGJIN SEMICHEM CO LTD | 2010-02-17 | — | — | CN | claimed |
| US-20250099539-A1 | METHODS AND COMPOSITIONS FOR REGENERATING HAIR CELLS AND/OR SUPPORTING CELLS | MASSACHUSETTS EYE AND EAR INFIRMARY | 2025-03-27 | — | — | US | disclosed |
| US-12239651-B2 | Treatment of hearing loss | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2025-03-04 | — | — | US | disclosed |
| US-20240409939-A1 | COMBINATION OF OLIGONUCLEOTIDES FOR MODULATING RTEL1 AND FUBP1 | HOFFMANN-LA ROCHE INC. | 2024-12-12 | — | — | US | disclosed |
| US-12156899-B2 | Methods and compositions for regenerating hair cells and/or supporting cells | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2024-12-03 | — | — | US | disclosed |
| EP-4448106-A1 | COMBINATION OF OLIGONUCLEOTIDES FOR MODULATING RTEL1 AND FUBP1 | Hoffmann-La Roche Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2012055170-A1 | USE OF CYTOPLASMIC C-MYC FOR REGULATING IMMUNE RESPONSES | THE UNIVERSITY OF HONG KONG (CN) | 2012-05-03 | — | — | WO | disclosed |
| US-20120107317-A1 | USE OF CYTOPLASMIC C-MYC FOR REGULATING IMMUNE RESPONSES | THE UNIVERSITY OF HONG KONG (CN) | 2012-05-03 | — | — | US | disclosed |
| CN-101648871-A | Optically active benzoate compound and preparation method thereof | DONGJIN SEMICHEM CO LTD | 2010-02-17 | — | — | CN | disclosed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409939-A1 | COMBINATION OF OLIGONUCLEOTIDES FOR MODULATING RTEL1 AND FUBP1 | FUBP1, TERF2IP, FUBP3 | AKR1C3 4009/4885GAA 3809/4885MAPT 2683/4885 |
| US-12156899-B2 | Methods and compositions for regenerating hair cells and/or supporting cells | HES1, NOTCH1, NOTCH4 | AKR1C3 2652/4885GAA 4768/4885MAPT 3747/4885 |
| US-20250099539-A1 | METHODS AND COMPOSITIONS FOR REGENERATING HAIR CELLS AND/OR SUPPORTING CELLS | HES1, NOTCH1, NOTCH4 | AKR1C3 2652/4885GAA 4768/4885MAPT 3747/4885 |
| US-20150238613-A1 | Compositions With Reduced Bitter Taste Perception | TAS2R50, TAS2R20, TAS2R4 | AKR1C3 4477/4885GAA 2168/4885MAPT 386/4885 |
| US-12239651-B2 | Treatment of hearing loss | HES1, NOTCH1, NOTCH4 | AKR1C3 3995/4885GAA 4549/4885MAPT 3170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.