Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.47 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488174 | 1.00 | MET (0.47) | METMAP4K3CHEK2S1PR1PDCD1 | |
| SCHEMBL488533 | 0.96 | MET (0.53) | METMAP4K3CHEK2 | |
| SCHEMBL30452957 | 0.96 | MET (0.53) | METMAP4K3CHEK2 | |
| SCHEMBL30453377 | 0.96 | MET (0.50) | METMAP4K3CHEK2JAK2JAK3 | |
| SCHEMBL487733 | 0.96 | MET (0.50) | METMAP4K3CHEK2JAK2JAK3 | |
| SCHEMBL30453407 | 0.92 | MET (0.56) | METMAP4K3CHEK2 | |
| SCHEMBL488484 | 0.92 | MET (0.56) | METMAP4K3CHEK2 | |
| SCHEMBL30453827 | 0.89 | MET (0.51) | METMAP4K3CHEK2 | |
| SCHEMBL488603 | 0.89 | MET (0.51) | METMAP4K3CHEK2 | |
| SCHEMBL488234 | 0.89 | MET (0.51) | METMAP4K3CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599890-A2 | SUNITINIB FOR PREVENTING AND/OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | Kyoto University (JP) | 2025-08-13 | — | — | EP | disclosed |
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |