Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.64 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487636 | 1.00 | MET (0.64) | METMAP4K4CSF1RPTK2KCNH2 | |
| SCHEMBL10217053 | 0.90 | MET (0.51) | METCSF1R | |
| SCHEMBL487790 | 0.87 | MET (0.68) | METCSF1R | |
| SCHEMBL488052 | 0.87 | MET (0.65) | METMAP4K4CSF1R | |
| SCHEMBL30453821 | 0.87 | MET (0.65) | METMAP4K4CSF1R | |
| SCHEMBL30453146 | 0.85 | MET (0.63) | METMAP4K4KCNH2 | |
| SCHEMBL488098 | 0.85 | MET (0.63) | METMAP4K4KCNH2 | |
| SCHEMBL488164 | 0.84 | MET (0.61) | MET | |
| SCHEMBL30453385 | 0.84 | MET (0.61) | MET | |
| SCHEMBL30454114 | 0.84 | MET (0.61) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |