Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.54 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | ATR | Q13535 | 9/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 2/20 | 0.40 |
| ▸ | LDHB | P07195 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488230 | 1.00 | MET (0.54) | METCHEK2ATRMAP4K3JAK2 | |
| SCHEMBL488797 | 0.92 | MET (0.58) | METCHEK2ATRMAP4K3JAK2 | |
| SCHEMBL30453966 | 0.92 | MET (0.58) | METCHEK2ATRMAP4K3JAK2 | |
| SCHEMBL488338 | 0.92 | MET (0.67) | METCHEK2MAP4K3JAK2 | |
| SCHEMBL30453773 | 0.92 | MET (0.67) | METCHEK2MAP4K3JAK2 | |
| SCHEMBL488646 | 0.90 | MET (0.60) | METCHEK2ATRMAP4K3LDHA | |
| SCHEMBL30453954 | 0.90 | MET (0.60) | METCHEK2ATRMAP4K3LDHA | |
| SCHEMBL488710 | 0.86 | MET (0.50) | METCHEK2ATRMAP4K3LDHA | |
| SCHEMBL30453644 | 0.86 | MET (0.50) | METCHEK2ATRMAP4K3LDHA | |
| SCHEMBL488713 | 0.86 | MET (0.50) | METCHEK2ATRMAP4K3LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |