Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 16/20 | 0.79 |
| ▸ | JAK2 | O60674 | 3/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.57 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.56 |
| ▸ | PLK4 | O00444 | 2/20 | 0.56 |
| ▸ | AURKA | O14965 | 2/20 | 0.56 |
| ▸ | DCLK1 | O15075 | 2/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.56 |
| ▸ | INSR | P06213 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | FES | P07332 | 2/20 | 0.56 |
| ▸ | CSF1R | P07333 | 2/20 | 0.56 |
| ▸ | LYN | P07948 | 2/20 | 0.56 |
| ▸ | RET | P07949 | 2/20 | 0.56 |
| ▸ | IGF1R | P08069 | 2/20 | 0.56 |
| ▸ | ROS1 | P08922 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | FER | P16591 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487761 | 1.00 | MET (0.79) | METJAK2ALKMAP4K3PLK4 | |
| SCHEMBL487763 | 1.00 | MET (0.79) | METJAK2ALKMAP4K3PLK4 | |
| SCHEMBL30454058 | 1.00 | MET (0.79) | METJAK2ALKMAP4K3PLK4 | |
| SCHEMBL488096 | 1.00 | MET (0.79) | METJAK2ALKMAP4K3PLK4 | |
| SCHEMBL30453564 | 0.95 | MET (0.84) | METJAK2ALKMAP4K3PLK4 | |
| SCHEMBL488370 | 0.95 | MET (0.84) | METJAK2ALKMAP4K3PLK4 | |
| SCHEMBL30453423 | 0.95 | MET (0.72) | METJAK2ALKMAP4K3PLK4 | |
| SCHEMBL30453486 | 0.95 | MET (0.72) | METJAK2ALKMAP4K3PLK4 | |
| SCHEMBL488048 | 0.95 | MET (0.72) | METJAK2ALKMAP4K3PLK4 | |
| SCHEMBL488489 | 0.95 | MET (0.72) | METJAK2ALKMAP4K3PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |